αVβ5 and CD44 Are Oxygen-Regulated Human Embryonic Stem Cell Attachment Factors
Figure 4
Nanog and Oct-4 nuclear colocalisation after surface receptor blockage. Quantification of nuclear-associated expression of Oct-4 and Nanog expression in hESCs which retained substrate adhesion after (a) αVβ5 blockage in either 2% O2 or 21% O2 cultured hESC and (b) CD44 blockage in either 2% O2 or 21% O2 cultured hESC. ***. -axis indicates % of nuclear colocalisation.