TrkAIII Promotes Microtubule Nucleation and Assembly at the Centrosome in SH-SY5Y Neuroblastoma Cells, Contributing to an Undifferentiated Anaplastic Phenotype
Figure 5
(a) Western blots demonstrating the relative levels of TrkAI, TrkAIII, and total tyrosine phosphorylated α-tubulins in a representative α-tubulin phosphorylation assay; (b) IF images demonstrating the difference in tubulin polymerisation induced by TrkAIII but not control or TrkAI immunoprecipitates in a representative tubulin polymerisation assay, in the presence but not in the absence of ATP.
