Environmental Lead Exposure Accelerates Progressive Diabetic Nephropathy in Type II Diabetic Patients
Table 3
Sensitivity analysis of renal function from month 18 to month 24 of the observation period ().
Renal function
Low BLB group
High BLB group
(95% CI)
(mL/min/1.73 m2)
()
()
Month 18
Ccr
32.8 ± 13.6
24.9 ± 10.7
0.005 (−13.2–−2.5)
D-GFR
32.4 ± 11.1
24.2 ± 8.1
<0.001 (−12.4–−4.1)
Month 24
Ccr
32.6 ± 16.1
21.5 ± 9.8
<0.001 (−16.9–−5.4)
D-GFR
30.2 ± 11.1
21.5 ± 7.5
<0.001 (−12.7–−4.7)
Total decrease of renal function (mL/min/1.73 m2) during the 2-year observation period
Ccr
12.2 ± 14.6
18.6 ± 11.2
0.010 (0.7–12.0)#
D-GFR
12.3 ± 11.5
19.3 ± 8.4
0.006 (2.7–11.3)#
Data were measured by the Student’s -test except # data by Mann-Whitney method.
means significant differences. Ccr: creatinine clearance; D-GFR: estimated GFR for Chinese patients with type II diabetes.
