Acetylsalicylic Acid Reduces the Severity of Dextran Sodium Sulfate-Induced Colitis and Increases the Formation of Anti-Inflammatory Lipid Mediators
Figure 3
Postmortem assessment of colitis severity. (a) Hematoxylin and eosin stains of transmural colon walls. Representative images of control tissue as compared to animals treated with DSS and ASA + DSS. (b) Colon shortening as an indicator of disease severity was compared between the different experimental groups, for the ASA-group and for the DSS group; * versus DSS. (c) Histological grading score, for the ASA-group and for the DSS group; ns versus DSS. Untreated controls (not shown) reached a maximum of 2 points in this score.
