Research Article
The SDF-1α3′ A Genetic Variation Is Correlated with Susceptibility of Asthma in Iranian Patients
Table 1
Subjects characteristics.
| | Variant | Controls | Asthma patients |
| | Age | 48 ± 12 years | 51 ± 11 years | | Gender: M/F | 88/101 (189) | 99/129 (228) | Frequent symptoms
(cough, wheeze, and shortness of breath) | − | + | | History of allergy | − | 70.3% | | Familial history of asthma | − | 43.2% | | FEV1 (predicted %) | 87.3 ± 14 | 79.2 ± 21 | | FEV1/FVC | 88.1 ± 9 | 82.3 ± 9 | | PEF (L/predicted %) | 91.6 ± 21 | 74.6 ± 19 | | FEF.sub.25–75> | 84.7 ± 17 | 62.9 ± 34 | | FVC (L/predicted %) | 93.4 ± 8 | 79.9 ± 19 | | Eosinophils (106/L) | 117 ± 96 | 612 ± 837 | | IgE (IU/mL) | 24 ± 9 | 1,112 ± 1,082 |
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FEV1: forced expiratory volume in 1 second, FVC: forced vital capacity, PEF: peak expiratory flow, and FEF.sub.25–75>: forced expiratory flow 25–75% or 25–50% (mean ± SD).
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