Site-Specific Distribution of CD68-Positive Microglial Cells in the Brains of Human Midterm Fetuses: A Topographical Relationship with Growing Axons
Figure 6
A GAP43-positive developing fiber tract does not contain CD68-positve cells. A brain at 15 weeks. Panel (a) (GAP43 immunohistochemistry) includes the optic nerve (OPN) and an early form of the pyramidal tract (center of the panel, obliquely running). Panels (b) and (c) correspond to higher magnification view of squares in panel (a). Star in panels (a) and (b) indicates a candidate of the anterior commissure. The pyramidal tract expresses GAP43 strongly (panel (a)), but it does not contain CD68-positve cells (panel (b)). In contrast, an area adjacent to the optic tract (asterisk in panels (a) and (c)) contained a cluster of CD68-positve cells (panel (c)).
