Distribution of ABO Blood Group and Major Cardiovascular Risk Factors with Coronary Heart Disease

Table 3

Distribution of major cardiovascular risk factors in all samples (𝑛=500) in accordance with ABO blood groups.

Variables (mean (SD))	Blood group				Test for; heterogeneity^1
	AB (𝑛=78)	A (𝑛=114)	B (𝑛=158)	O (𝑛=150)
TC (mg/dL)	174.08 (44.52)^2	181.24 (36.29)	185.28 (49.77)	174.96 (38.43)	𝑃=0.117
TG (mg/dL)	163.11 (39.02)	159.24 (64.28)	164.01 (66.02)	161.38 (59.03)	𝑃=0.928
HDL-c (mg/dL)	36.65 (12.04)	30.81 (5.78)^5	32.13 (7.39)^5	29.56 (8.11)^5	𝑃<0.0001
LDL-c (mg/dL)	104.80 (40.71)	118.58 (32.29)	120.34 (44.05)^4	112.78 (35.79)	𝑃=0.025
WC (cm)	85.55 (4.03)	86.62 (6.93)	86.04 (6.08)	86.56 (5.72)	𝑃=0.557
Smoker	25 (32.1%)^3	41 (36%)	78 (49.4%)	78 (52%)^4	𝑃=0.007
Alcohol user	9 (11.5%)	40 (35.1%)^5	36 (22.8%)	14 (9.3%)	𝑃<0.0001
Hypertension	25 (32.1%)	46 (40.9%)	66 (41.8%)	67 (44.7%)	𝑃=0.457
Family history	8 (10.3%)	27 (23.7%)	41 (25.9%)	43 (28.7%)^4	𝑃=0.037

¹Derived from analysis of covariance that evaluated the associations between major cardiovascular risk factors (dependent factor) and blood group (independent factor), after adjustment for age (in years) and sex.
²Mean (SD) (all such values).
³Number (percentage in individual group) (all such values).
^4,5Significantly different from AB blood group (ANOVA with Bonferroni’s correction): ⁴𝑃<0.05, ⁵𝑃<0.01.
A indicates A blood group; B indicates B blood group; O indicates O blood group; AB indicates AB blood group; TC: total cholesterol; TG: triglycerides; HDL-c: high density lipoprotein cholesterol; LDL-c: low density lipoprotein cholesterol; WC: waist circumference.