Molecular Characterization and In Silico Analysis of Naturally Occurring TEM Beta-Lactamase Variants among Pathogenic Enterobacteriaceae Infecting Indian Patients

Table 1

Characterization of bla _TEM variants identified in this study.

TEM types	Matched GenBank accession ID	Our accession ID	Enzyme type			Codon alterations compared to TEM-1
			Broad spectrum	ESBL	IRT	69	84	134	165	184	276
TEM-1	YP001928075	JN002395	+	−	−	ATG	GTT	GCT	TGG	GTC	AAT
TEM-116	AEJ08195	JF973688	+	−	−	CTG	ATT	−	−	GCC	−
TEM-1like	ACP18864	KC699843	+	−	−	−	−	−	GGG	−	−
TEM-169	ACP18864	KC699843	+	−	−	CTG	−	−	GGG	−	−
TEM-190	AEL88240	KC699842	+	−	−	CTG	−	−	GGG	−	GAT
TEM-33	AF190695	KC699843	−	−	+	CTG	−	GCG	GGG	−	−