BioMed Research International / 2013 / Article / Tab 3

Research Article

Molecular Characterization and In Silico Analysis of Naturally Occurring TEM Beta-Lactamase Variants among Pathogenic Enterobacteriaceae Infecting Indian Patients

Table 3

Bla TEM protein stability analysis at five differentiating amino acid positions.

Amino acid substitutionChange in solvent
accessibility (%)
Free folding energy change (ΔΔG) (kcal/mol)

Met69Leu12.0
Leu69Met0.55−3.82

Val84Ile24.72−0.48
Ile84Val15.14−1.86

Trp165Gly37.840.9
Gly165Trp34.31−1.61

Ala184Val27.220.59
Val184Ala15.61−1.25

Asn276Asp8.20.09
Asp276Asn9.72−1.59

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19.