Research Article

Integrative Analysis of Methylome and Transcriptome Reveals the Importance of Unmethylated CpGs in Non-CpG Island Gene Activation

Figure 4

Three potential models, describing the association between methylation and gene regulation. (a) Methyl binding repressors based model. (b) pG binding activators based model. (c) A combined model. The schematic graphs on the right represent the expected results according to each model.
785731.fig.004a
(a)
785731.fig.004b
(b)
785731.fig.004c
(c)