| | | Mild flare | Moderate flare | Severe flare |
| | Number of flares per patient per year (mean, SD) | 0.9 | 1.0 | 1.6 | 1.2 | 0.1 | 0.3 | | Number of patients with at least 1 flare during the entire followup (N, %) | 10,696 | 75% | 13,002 | 91% | 3,540 | 25% | | Number of months of followup (mean, SD) | 40.5 | 20.5 | 39.8 | 20.5 | 43.0 | 21.9 | | Number of flares per patient (mean, SD) | 2.8 | 3.0 | 5.2 | 4.5 | 0.4 | 0.9 | | Number of patients with only 1 flare (N, %) | 2,663 | 25% | 1,608 | 12% | 2,666 | 75% | | Number of patients with only 2 flares (N, %) | 2,110 | 20% | 1,698 | 13% | 464 | 13% | | Number of patients with 3+ flares (N, %) | 5,923 | 55% | 9,696 | 75% | 410 | 12% |
| | Cost per flare | Mean (SD) | Median | Mean (SD) | Median | Mean (SD) | Median |
| | Medical cost | $45 ($416) | $0 | $477 ($2,221) | $69 | $11,621 ($29,148) | $2,138 | | Pharmacy cost | $84 ($562) | $25 | $84 ($506) | $5 | $94 ($488) | $8 | | Total cost | $129 ($702) | $36 | $562 (2,275) | $123 | $11,716 ($29,141) | $2,294 |
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