Anti-Inflammatory Activity and Composition of Senecio salignus Kunth
Table 1
Anti-inflammatory effect of the chloroform extract of Senecio salignus on rat paw edema induced by carrageenan.
Time
Doses
Indomethacin
Doses of Senecio salignus
8 mg/kg
50 mg/kg
100 mg/kg
200 mg/kg
400 mg/kg
1 h
37.1 ± 3.9*
31.2 ± 4.8
35.7 ± 7.3*
32.4 ± 4.1*
48.1 ± 2*
2 h
62 ± 4.1*
50.8 ± 5.7*
56.1 ± 5.2*
55.4 ± 4.7*
56.8 ± 7*
3 h
63 ± 4.2*
56.7 ± 6.7*
54 ± 4*
60.6 ± 4.9*
64.1 ± 4*
4 h
57.9 ± 3.5*
40.8 ± 4.3*
51.1 ± 5*
60.1 ± 2.3*
59.7 ± 6.2*
5 h
66.8 ± 3.6*
38.5 ± 8.8
45.3 ± 4.2*
63.7 ± 5.6*
55.5 ± 5.9*
Results are expressed as percentage of inhibition and mean of eight determinations ± SE. One-way ANOVA, Dunnett test * () for the comparison of S. salignus with indomethacin-treated groups.
