Research Article

Dissolution of Silver Nanowires and Nanospheres Dictates Their Toxicity to Escherichia coli

Figure 3

Dose-dependent effects of Ag nanowires (NWs), Ag nanospheres, and AgNO3 on two recombinant Escherichia coli strains after 4h exposure. (a) Inhibition of the light output in bioluminescent E. coli; (c) induction of the bioluminescence of the Ag+-induced E. coli. Filled columns in (b) indicate EC50 values calculated from panel (a) (see horizontal dotted line); filled columns in (d) indicate induction threshold values calculated from panel (c) (see horizontal dotted line). Open columns in (b) and (d) with numerical values show mg of dissolved Ag/L at EC50 or induction threshold, respectively. Mean ± standard deviation of two independent experiments is shown: a—significant ( ) difference from AgNO3, b—significant ( ) difference from AgNO3 and Ag NW.
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(a)
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(b)
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(c)
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(d)