Research Article

The Cytotoxic Effect of Magainin II on the MDA-MB-231 and M14K Tumour Cell Lines

Table 1

The percentage of citostasis (the stop of the cell's proliferation and development until the cell death) was calculated as: (1−A) × 100 = % citostasis, where A = the ratio between cells' absorbance treated with peptide and absorbance of untreated cells. In this table we presented the results for the citostatsis of the human mammary adenocarcinoma line cells incubated for 72 hours with magainin II in RPMI.

Tumour cell lines MDA-MB-231 cytostasis % (MTT test)
Peptide concentrationMagainin II

120 μM59.44
60 μM23.54521
30 μM13.6974
15 μM−19.9642
7,5 μM−50.761
3,5 μM−59.9821
1,8 μM−62.6679
0,9 μM−64.906