Proliferative Activity in Libyan Breast Cancer with Comparison to European and Central African Patients

Table 1

Average estimates of mitotic activity in breast cancers (as SMI and MAI) in different subgroups of the 130 Libyan female breast cancer patients.

Group	No. of patients	SMI (SD)	𝑃 value	MAI (SD)	𝑃 value
Whole material	130	32.1 (20.9)		27.3 (18.5)
Age groups			0.02		0.001
<40	49	31.6 (14.0)		27.8 (17.3)
40–49	32	24.3 (19.2)		17.4 (14.6)
≥50	49	37.6 (26.0)		33.2 (20.0)
Menopausal status			0.01		0.008
Premenopausal; Postmenopausal	80; 50	28.5 (16.6); 37.7 (25.7)		23.9 (17.0); 32.7 (19.8)
Lymph node (LN) status			0.003		0.035
LN−	27	21.5 (13.0)		20.6 (19.7)
LN+	103	34.8 (21.8)		29.0 (17.9)
Histological grade			0.01		0.003
1	10	14.9 (9.2)		12.8 (9.6)
2	70	32.1 (19.3)		25.4 (17.1)
3	50	35.4 (23.3)		32.7 (20.0)
Histological type			0.7		0.8
Invasive  ductal carcinoma	95	32.7 (21.2)		26.9 (18.6)
Invasive  lobular carcinoma	13	32.9 (16.4)		30.1 (17.1)
Other types	22	28.7 (27.7)		27.7 (19.7)