Development of a Novel System for Mass Spectrometric Analysis of Cancer-Associated Fucosylation in Plasma α1-Acid Glycoprotein
Mass spectra of AGP glycans isolated from a healthy control and a patient with colon cancer. Black triangles indicate fucosylated tri- and tetra-antennary glycans assigned. Purified AGP was prepared and labeled from 500 μL of plasma samples and an each aliquot (ca. one-fiftieth) was used for MS analysis.
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