BioMed Research International / 2013 / Article / Fig 1

Research Article

Alleviation of Hyperglycemia Induced Vascular Endothelial Injury by Exenatide Might Be Related to the Reduction of Nitrooxidative Stress

Figure 1

The rats DM models had been successfully established and treatment with exenatide decreased fasting glucose levels in DM rats. (a) The changes of OGTT. High fat diet induced a significant increase in blood glucose levels in every time point. (b) Fasting insulin levels (FIns). High fat diet induced a significant increase in fasting insulin levels. (c) The changes of AUC. High fat diet induced a significant increase in AUC ( glucose). (d) HOMA insulin resistance (HOMA-IR). High fat diet induced a significant increase in HOMA-IR (HOMA-IR ( (mmol/L)/22.5). (e) Fasting glucose (FG) levels. DM induced a significant increase in fasting glucose levels, and treatment with exenatide for 45 days significantly decreased fasting glucose levels. In (a), (b), (c), and (d), CON and FD . In (e) CON ; DM, , and    . ** versus CON; ## versus DM, mean ± SEM.
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