Research Article
Molecular Profiling Predicts the Existence of Two Functionally Distinct Classes of Ovarian Cancer Stroma
Table 2
The 34 CS-expressed ligands with the 20 expressed Cepi receptors (a) and the 36 Cepi-expressed ligands with the 21 expressed CS receptors (b).
| (a) |
| | CS ligands | Cepi receptors | | Gene symbol | Probeset ID | Gene symbol | Probeset ID |
| |
***CXCL1 | 204470_at |
****CXCR4 | 217028_at | |
*CXCL3 | 207850_at |
**FGFR2 | 208228_s_at | |
***CXCL9 | 203915_at |
***FGFR3 | 204379_s_at | |
***CXCL10 | 204533_at |
**MET | 203510_at | |
***CXCL11 | 210163_at |
*TGFBR2 | 207334_s_at | |
***CXCL12 | 209687_at |
***TGFBR2 | 208944_at | |
***CXCL12 | 203666_at |
**TGFBR3 | 204731_at | |
***CXCL13 | 205242_at |
***TGFBR3 | 226625_at | |
**CXCL16 | 223454_at |
***PDGFRA | 203131_at | | CXCL17 | 226960_at |
*PDGFRA | 1554828_at | |
*FGF1 | 205117_at |
***IL1R1 | 202948_at | |
*FGF2 | 204422_s_at |
*IL1R1 | 215561_s_at | |
***FGF7 | 1554741_s_at |
*IL1R2 | 205403_at | |
*FGF9 | 239178_at |
**IL7R | 226218_at | |
**FGF9 | 206404_at |
**IL10RA | 204912_at | |
***FGF13 | 205110_s_at |
**FZD1 | 204451_at | |
*HGF | 210997_at |
**FZD2 | 210220_at | |
***IGF1 | 209540_at |
**FZD7 | 203705_s_at | |
*IGF2 | 202409_at |
***FZD7 | 203706_s_at | |
*TGFA | 205016_at |
**FZD10 | 219764_at | |
***TGFB2 | 209909_s_at | | | |
*PDGFA | 205463_s_at | | | |
***PDGFD | 219304_s_at | | | |
*IL7 | 206693_at | | | |
***IL15 | 205992_s_at | | | |
**IL16 | 209828_s_at | | | |
**IL17D | 227401_at | | | |
**IL18 | 206295_at | | | |
**WNT2B | 206458_s_at | | | |
*WNT7A | 210248_at | | | |
***WNT5A | 213425_at | | | |
***VEGFA | 210512_s_at | | | |
*VEGFA | 210513_s_at | | | |
*VEGFA | 211527_x_at | | |
|
|
| (b) |
| | Cepi ligands | CS receptors | | Gene symbol | Probeset ID | Gene symbol | Probeset ID |
| |
***CXCL1 | 204470_at |
****CXCR4 | 217028_at | |
**CXCL3 | 207850_at |
**FGFR2 | 208228_s_at | |
***CXCL9 | 203915_at |
*FGFR3 | 204379_s_at | |
***CXCL10 | 204533_at | IL12RB1 | 1552584_at | |
***CXCL11 | 210163_at |
***IL1R1 | 202948_at | |
*CXCL12 | 203666_at |
***TGFBR2 | 208944_at | |
*CXCL12 | 209687_at |
***TGFBR3 | 204731_at | |
**CXCL13 | 205242_at |
***TGFBR3 | 226625_at | |
**CXCL16 | 223454_at |
***PDGFRA | 203131_at | | CXCL17 | 226960_at |
**PDGFRA | 215305_at | |
*FGF1 | 205117_at |
***MET | 203510_at | |
***FGF9 | 206404_at |
**IL1R1 | 215561_s_at | |
***FGF9 | 239178_at |
*IL1R2 | 205403_at | |
*FGF11 | 227271_at |
**IL7R | 226218_at | |
***FGF18 | 231382_at |
**IL10RA | 204912_at | |
*FGF18 | 211029_x_at |
*IL21R | 221658_s_at | |
*FGF18 | 206987_x_at |
**FZD1 | 204451_at | |
**FGF18 | 214284_s_at |
**FZD2 | 210220_at | |
**TGFA | 205016_at |
***FZD7 | 203705_s_at | |
**TGFB2 | 209909_s_at |
**FZD7 | 203706_s_at | |
**PDGFA | 205463_s_at |
***FZD10 | 219764_at | |
***PDGFD | 219304_s_at | | | |
***IGF1 | 209540_at | | | |
*IL7 | 206693_at | | | |
*IL1B | 39402_at | | | |
***IL15 | 205992_s_at | | | |
**IL18 | 206295_at | | | |
**WNT2 | 205648_at | | | |
**WNT2B | 206458_s_at | | | |
***WNT5A | 213425_at | | | |
*WNT7A | 210248_at | | | |
**WNT11 | 206737_at | | | |
***VEGFA | 210512_s_at | | | |
***VEGFA | 210513_s_at | | | |
*VEGFA | 211527_x_at | | | |
**VEGFA | 212171_x_at | | |
|
|
Significance of detection calls: , , and .
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