TLR Stimulation of Bone Marrow Lymphoid Precursors from Childhood Acute Leukemia Modifies Their Differentiation Potentials

Figure 6

Rapid formation of CD14⁺ myeloid cells from T-ALL progenitors upon responsiveness to TLR4 signals. Long-term cultures (30 d) were conducted to assess CD14⁺ cell formation. While maintenance of CD7⁺ cells was unaltered, CD34⁻CD7⁻CD14⁺ tended to increase with the LPS treatment (middle panel).