Changes in Otx2 and Parvalbumin Immunoreactivity in the Superior Colliculus in the Platelet-Derived Growth Factor Receptor-β Knockout Mice
High-magnification photomicrographs of the PV-labeled sections in the superficial layers (A), IGR (B) and DL (C) of the control (A) and KO (B) mouse SC. Note a dense band in the deep SGR and the upper OP (open triangles) (A), clusters of PV-IR cells (arrows) and the intense PV-IR neuropils (open triangles) in the IGR (B), and scattered PV-IR cells (arrows) in the DL (C) in the control mouse (a). Similar patterns of distribution of PV-IR cells are also observed in the KO mice (b), but fewer PV-IR cells and less intense PV-IR neuropils are observed. Orientation of the images dorsal to the top and lateral to the left. SGR superficial gray; OP optic; IGR intermediate gray layer; is DL and the deep layers. Scale bar = 60 μm.
(a) Control (PV)
(b) KO (PV)
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