Research Article

Changes in Otx2 and Parvalbumin Immunoreactivity in the Superior Colliculus in the Platelet-Derived Growth Factor Receptor-β Knockout Mice

Table 1

Comparison of number of Otx2-IR cells in the SC between the control (C1–6) and PDGFR-β KO (K1–4) mice.

SC subfieldControlPDGFR- KO
No. of cells per sectionNo. of cells per section
C1C2C3C4C5C6Mean ± SDK1K2K3K4Mean ± SD%Change value

ZO224.8214.0246.2203.8223.3234.8 153.8157.5160.8156.8 −30.0%0.001
SGR378.8358.7376.0401.0391.8454.2 240.5271.2231.0239.3 −37.6%0.001
OP325.5385.7399.0330.3350.0354.7 269.3280.0247.5261.0 −25.2%0.001
IGR316.2316.2302.0279.2328.5299.8 214.7229.0220.7216.7 −28.2%0.001
DL189.8168.8258.2159.2268.7272.3 176.3138.3147.0159.2 −29.3%0.048

For each layer of the SC, the mean numbers of cells per section in each animal are indicated. In each animal, 6 sections were examined. %Change and value indicate %change from the control mice and statistical significance from the control mice (unpaired -test) in each layer. ZO: zonal layer; SGR: superficial gray layer; OP: optic layer; IGR: intermediate gray layer; and DL: deep layer.