Review Article
Extremophilic SHMTs: From Structure to Biotechnology
Table 2
Comparison of the kinetic parameters of the reactions catalyzed by different SHMTs.
| Substrate | E. coli SHMTa | SHMTa P. ingrahamii | B. stearothermophilus SHMTb | (mM) | (min−1) | (mM) | (min−1) | (mM) | (s−1) |
| L-Threonine | 43d | 4.3d | 20.2f | 6.6f | NDc | NDc | L-Threo-phenylserine | 19d | 167d | 17.2f | 852f | NDc | NDc | L-Allo-threonine | 1.5e | 30e | 1.6f | 107f | 0.9g | 0.47g | L-Serine | 0.3e | 640e | 0.4f | 555f | 0.9g | 3.9g |
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Reactions were carried out at 30°C
bReactions were carried out at 37°C
cNot determined
dFrom [25]
eFrom [53]
fFrom [54]
gFrom [48].
|