Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2013 (2013), Article ID 852093, 11 pages
http://dx.doi.org/10.1155/2013/852093
Review Article

Heparan Sulfate and Heparanase as Modulators of Breast Cancer Progression

1Programa de Glicobiologia, Instituto de Bioquímica de Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil
2Laboratório de Bioquímica e Biologia Celular de Glicoconjugados, Hospital Universitário Clementino Fraga Filho, Rua Prof. Rodolpho P. Rocco No. 255, 4 andar, sala 4A-08, Rio de Janeiro, RJ 21941-590, Brazil

Received 10 June 2013; Accepted 4 July 2013

Academic Editor: Davide Vigetti

Copyright © 2013 Angélica M. Gomes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [19 citations]

The following is the list of published articles that have cited the current article.

  • Teresa Cristina Fernandes dos Santos, Angelica Maciel Gomes, Marcos Eduardo Machado Paschoal, Mariana Paranhos Stelling, Vivian Mary Barral Dodd Rumjanek, Alyson do Rosario Junior, Paulo Marcos Valiante, Kalil Madi, Heitor Siffert Pereira de Souza, Mauro Sergio Goncalves Pavao, and Morgana Teixeira Lima Castelo-Branco, “Heparanase expression and localization in different types of human lung cancer,” Biochimica et Biophysica Acta-General Subjects, vol. 1840, no. 8, pp. 2599–2608, 2014. View at Publisher · View at Google Scholar
  • Yueqin Guo, Zhouhua Li, and Xinhua Lin, “Hs3st-A and Hs3st-B regulate intestinal homeostasis in Drosophila adult midgut,” Cellular Signalling, 2014. View at Publisher · View at Google Scholar
  • Edward Hammond, Ashwani Khurana, Viji Shridhar, and Keith Dredge, “The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics,” Frontiers in Oncology, vol. 4, 2014. View at Publisher · View at Google Scholar
  • Dabei Tang, Ying Piao, Shu Zhao, Xudong Mu, Shuo Li, Wenjie Ma, Ying Song, Jingxuan Wang, Wenhui Zhao, and Qingyuan Zhang, “Expression and correlation of matrix metalloproteinase-9 and heparanase in patients with breast cancer,” Medical Oncology, vol. 31, no. 7, 2014. View at Publisher · View at Google Scholar
  • Atit Silsirivanit, Kanlayanee Sawanyawisuth, Gregory J. Riggins, and Chaisiri Wongkham, “Cancer biomarker discovery for cholangiocarcinoma: the high-throughput approaches,” Journal of Hepato-Biliary-Pancreatic Sciences, 2014. View at Publisher · View at Google Scholar
  • Angelica Maciel Gomes, Eliene Oliveira Kozlowski, Lubor Borsig, Felipe C. O. B. Teixeira, Israel Vlodavsky, and Mauro S. G. Pavao, “Antitumor properties of a new non-anticoagulant heparin analog from the mollusk Nodipecten nodosus: Effect on P-selectin, heparanase, metastasis and c,” Glycobiology, vol. 25, no. 4, pp. 386–393, 2015. View at Publisher · View at Google Scholar
  • E. P. Cunha, L. M. Pompei, T. R. Theodoro, M. L. Steiner, V. F. Silva, E. R. A. Silveira, A. M. A. A. Mader, M. A. S. Pinhal, and C. E. Fernandes, “Is expression of rat breast matrix components influenced by estrogen, progestins and tibolone?,” Climacteric, pp. 1–5, 2015. View at Publisher · View at Google Scholar
  • Achilleas D. Theocharis, Spyros S. Skandalis, Thomas Neill, Hinke A.B. Multhaupt, Mario Hubo, Helena Frey, Sandeep Gopal, Angélica Gomes, Nikos Afratis, Hooi Ching Lim, John R. Couchman, Jorge Filmus, Sanderson Ralph D., Liliana Schaefer, Renato V. Iozzo, and Nikos K. Karamanos, “Insights into the key roles of proteoglycans in breast cancer biology and translational medicine,” Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2015. View at Publisher · View at Google Scholar
  • Alex Langford-Smith, Anthony J. Day, Paul N. Bishop, and Simon J. Clark, “Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation,” Frontiers in Immunology, vol. 6, 2015. View at Publisher · View at Google Scholar
  • Jacob Insua-Rodríguez, and Thordur Oskarsson, “The extracellular matrix in breast cancer,” Advanced Drug Delivery Reviews, 2015. View at Publisher · View at Google Scholar
  • Michael S. Shawky, Carmela Ricciardelli, Megan Lord, John Whitelock, Vito Ferro, Kara Britt, and Erik W. Thompson, “Proteoglycans: Potential Agents in Mammographic Density and the Associated Breast Cancer Risk,” Journal of Mammary Gland Biology and Neoplasia, 2015. View at Publisher · View at Google Scholar
  • Pattaya Seeree, Phorutai Pearngam, Supeecha Kumkate, and Tavan Janvilisri, “An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma,” International Journal of Genomics, vol. 2015, pp. 1–16, 2015. View at Publisher · View at Google Scholar
  • Karel Smetana, Pavol Szabo, Peter Gál, Sabine André, Hans-Joachim Gabius, Ondřej Kodet, and Barbora Dvořánková, “Emerging role of tissue lectins as microenvironmental effectors in tumors and wounds,” Histology and Histopathology, vol. 30, no. 3, pp. 293–309, 2015. View at Publisher · View at Google Scholar
  • Jlenia Brunetti, Lorenzo Depau, Chiara Falciani, Mariangela Gentile, Elisabetta Mandarini, Giulia Riolo, Pietro Lupetti, Alessandro Pini, and Luisa Bracci, “Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe,” Scientific Reports, vol. 6, pp. 27174, 2016. View at Publisher · View at Google Scholar
  • Manuela Viola, Kathrin Brüggemann, Evgenia Karousou, Ilaria Caon, Elena Caravà, Davide Vigetti, Burkhard Greve, Christian Stock, Giancarlo De Luca, Alberto Passi, and Martin Götte, “MDA-MB-231 breast cancer cell viability, motility and matrix adhesion are regulated by a complex interplay of heparan sulfate, chondroitin−/dermatan sulfate and hyaluronan biosynthesis,” Glycoconjugate Journal, 2016. View at Publisher · View at Google Scholar
  • Shirin Mahmoodi, Navid Nezafat, Manica Negahdaripour, Nosratollah Zarghami, Abolfazl Barzegar, Ali R. Nikanfar, and Younes Ghasemi, “Harnessing bioinformatics for designing a novel multiepitope peptide vaccine against breast cancer,” Current Pharmaceutical Biotechnology, vol. 17, no. 12, pp. 1100–1114, 2016. View at Publisher · View at Google Scholar
  • John Hwan Lee, Yoojin Kim, Ye-Eun Yoon, Yong-Jin Kim, Seong-Geun Oh, Jae-Hyung Jang, and Eunmi Kim, “Development of efficient adeno-associated virus (AAV)-mediated gene delivery system with a phytoactive material for targeting human melanoma cells,” New Biotechnology, vol. 37, pp. 194–199, 2017. View at Publisher · View at Google Scholar
  • Hao Jin, and Shaobo Zhou, “The functions of heparanase in human diseases,” Mini-Reviews in Medicinal Chemistry, vol. 17, no. 6, pp. 541–548, 2017. View at Publisher · View at Google Scholar
  • Hao Jin, Shaobo Zhou, Song Yang, and Hai-ming Cao, “Heparanase overexpression down-regulates syndecan-1 expression in a gallbladder carcinoma cell line,” Journal of International Medical Research, vol. 45, no. 2, pp. 662–672, 2017. View at Publisher · View at Google Scholar