Coagulation Proteins Influencing Global Coagulation Assays in Cirrhosis: Hypercoagulability in Cirrhosis Assessed by Thrombomodulin-Induced Thrombin Generation Assay
Figure 1
Endogenous thrombin potential (ETP) ratios of healthy controls () and cirrhotic patients (). The ETP ratio was calculated by dividing “ETP with thrombomodulin (TM)” by “ETP without TM” multiplied by 100. The concentrations of TM were 2.5 nM for 1 pM tissue factor stimulation and 5 nM for 5 pM tissue factor stimulation. (a) With 1 pM tissue factor stimulation, the ETP ratio was significantly higher in the patients with cirrhosis (). (b) With 5 pM tissue factor stimulation, there was no significant difference in the ETP ratio between the controls and patients with cirrhosis.
