Clinical Study

Prevalence of Occult Hepatitis B Virus Infection in a Cohort of HIV-Positive Patients Resident in Sicily, Italy

Table 1

Socio-demographic and serological characteristics of 405 HBsAg-negative/HIV-infected individuals.

Characteristic ( (%), by column)No HBV markersAnti-HBs + Anti-HBcAnti-HBc aloneAnti-HBs aloneAnti-HCV

Study population (% by row)405183 (45.2)88 (21.7)71 63 (15.6)98
Sex
 Male275 (67.9)125 (68.5)59 (66.7)50 (70.4)41 (64.1)75 (76.5)
 Female130 (32.1)58 (31.5)29 (33.3)21 (29.6)22 (35.9)23 (23.5)
 M : F ratio2.12.12.02.41.93.3
Age (years, median (IQR))41.0 (14.2)41.0 (12.5)43.9 (14.4)43.8 (11.2)32.0 (20.2)45.1 (5.8)
 ≤20 years15 (3.7)6 (3.3)3 (3.4)2 (2.8)4 (6.3)1 (1.0)
 21–30 years63 (15.5)23 (12.6)8 (9.1)7 (9.9)25 (39.7)3 (3.1)
 31–40 years108 (26.7)57 (31.1)24 (27.3)15 (21.1)12 (19.0)13 (13.3)
 ≥41 years219 (54.1)97 (53.0)53 (60.2)47 (66.2)22 (34.9)81 (82.7)
Mode of HIV transmission
 Heterosexual197 (48.6)92 (50.3)34 (38.6)40 (56.3)31 (49.2)35 (35.7)
 Homosexual121 (29.9)63 (34.4)24 (27.3)9 (12.7)25 (39.7)15 (15.3)
 IVDU71 (17.5)21 (11.5)23 (26.1)21 (29.6)6 (9.5)44 (44.9)
 Other/unknown16 (4.0)7 (3.8)7 (8.0)1 (1.4)1 (1.6)4 (4.1)
Geographic origin
 Italy335 (82.7)160 (87.4)67 (76.1)51 (71.8)57 (90.5)91 (92.9)
 Africa63 (15.6)20 (10.9)17 (19.3)20 (28.2)6 (9.5)7 (7.1)
 Eastern Europe4 (1.0)2 (1.1)2 (2.3)0 (0)0 (0)0 (0)
 Other3 (0.7)1 (0.5)2 (2.3)0 (0)0 (0)0 (0)

*Anti-HCV positive versus anti-HCV negative = 38.8% versus 10.7% (OR = 5.3, CI95%: 3.0–9.3, ).
/405 (7.2%): HIV/HCV coinfected subjects negative to all of the serological markers of HBV infection.
IVDU: Intravenous drug use.