7,8-Dihydroxyflavone Suppresses Oxidative Stress-Induced Base Modification in DNA via Induction of the Repair Enzyme 8-Oxoguanine DNA Glycosylase-1
Figure 1
DHF reduces H2O2-induced 8-oxoG formation. (a) Cells were treated with 40 μM DHF for 1 h and then incubated with 1 mM H2O2 for an additional 24 h. *Significantly different from control cells (); #significantly different from H2O2-treated cells (). (b) Binding of avidin-TRITC, which reflects 8-oxoG levels, was visualized with a fluorescence microscope.
