Genotyping of Clinical Mycobacterium tuberculosis Isolates Based on IS6110 and MIRU-VNTR Polymorphisms

Table 1

Comparison of clustering in M. tuberculosis strains by the use of 15-locus MIRU-VNTR and FLiP typing methods.

MIRU-VNTR		FLiP pattern (no. of strains)	MIRU-VNTR		FLiP pattern; (no. of strains)
Pattern; (no. of strains)	Numerical code^a		Pattern; (no. of strains)	Numerical code^a
1 (11)	453531333243437	1 (6), 2 (1), 3 (1),; 4 (2), 5 (1), 6 (1)	16 (2); 17 (2)	423533332242325; 432433343242325	30 (1), 31 (1); 32 (2)
2 (7)	482132544343228	7 (12)^b	18 (2)	443433343242225	33 (2)
3 (6)	453533333443335	8 (3), 9 (1), 10 (1),; 11 (1)	19 (2); 20 (2)	423434343242526; 433334343242626	34 (1), 35 (1); 36 (2)
4 (4)	343541333431446	12 (5)	21 (2)	432335343242525	37 (2)
5 (2)	443533333443437	13 (2)	22 (2)^d	431535342232322	38 (2)^d
6 (2)	453533333443337	14 (2)	23 (2)	443444333443545	39 (2)
7 (2)	432433333443437	15 (1), 16 (1)	24 (2)	3112132345443138	40 (1), 41 (1)
8 (2)	463634333443637	17 (1), 18 (1)	25 (2)	4102123454443226	42 (2)
9 (2)	433533333443637	19 (1), 20 (1)	26 (2)	492134544443138	43 (1), 44 (1)
10 (2)^c	442431542132437	21 (2)^c	27 (2)	482532544343228	7 (2)^b
11 (2)	453531333243237	7 (1)^b, 22 (1)	28 (1), 29 (1)	453533333443345,	45 (2)
12 (2)	453531333443437	23 (2)		453533333443342
13 (2)	463633333443235	24 (1), 25 (1)	30 (1), 31 (1)	453533333475347,	46 (2)
14 (2)	423432342242425	26 (1), 27 (1)		453543333463248
15 (2)	432532342242425	28 (1), 29 (1)

aNumber of copies > 9 per locus is underlined.
^bMembers (𝑛=12) of the same cluster (FLiP pattern 7).
^{c, d}Sequential isolates from two patients.