Gene Expression Profiling of Human Oocytes Developed and Matured In Vivo or In Vitro

Table 1

Analyses of human oocyte gene expression by RT-PCR.

Oocyte gene expression analyses by RT-PCR
Analyzed oocytes	Maturity of oocytes	Expression of genes	Functions of analyzed genes	Study
Four oocytes, forty-two embryos	MII, non-fertilized	High expression of BRCA1, BRCA2, ATM, TP53, RB1, MNAD2, BUB1, APC, beta-actin in oocytes, but low in embryos	Genes related to the preimplantation development	Wells et al., 2005 [17]
Four single oocytes, five embryos	MII, non-fertilized	LDH-A, LDH-B, LDH-C expression in oocytes and embryos	Genes encoding lactate dehydrogenase isozymes
		SUMO-1, SUMO-2, SUMO-3 expression in oocytes and embryos	Small ubiquitin-like modifier isoforms	Li et al., 2006 [18]
Oocytes from; follicles	From primordial follicles to MII oocytes	NOBOX expression from primordial follicles to MII oocytes	Homeobox genes encoding transcription factors
	From primordial to early primary follicles	HOXA10 expression from primordial to early primary follicles
	From primordial follicles to GV oocytes	HOXB7 expression from primordial follicles to GV oocytes
	GV oocytes	HOXA7 expression in GV oocytes		Huntriss et al.,; 2006 [19]
	MII oocytes	HOXA1, HEX expression in MII oocytes
	Cumulus cells	HOXC9, HOXC8, HOXC6, HOXA7, HOXA5, HOXA4 expression in cumulus cells