|
| Genes significantly overexpressed in oocytes |
| Gene symbol | Gene title | Chromosome |
|
| Gamete markers |
| DAZL | Deleted in azoospermia-like | 3 |
| DDX4/VASA | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 5 |
| DPPA3/STELLA | Developmental pluripotency associated 3 | 12 |
|
| Embryogenesis, pluripotency, self-renewal, proliferation, development |
| ZAR1 | Zygote arrest 1 | 4 |
| PUM1 | Pumilio homolog 1 (Drosophila) | 1 |
| PUM2 | Pumilio homolog 2 (Drosophila) | 2 |
| NANOS1 | Nanos homolog 1 (Drosophila) | 10 |
| NANOG | Nanog homeobox | 12 |
| SOX2 | SRY (sex determining region Y)-box 2 | 3 |
| SALL2 | Sal-like 2 (Drosophila) | 14 |
| KLF4 | Kruppel-like factor 4 (gut) | 9 |
| LIN28B | Lin-28 homolog B (C. elegans) | 6 |
|
| Maturation promoting and related factors |
| CCNB1 | Cyclin B1 | 5 |
| CCNB2 | Cyclin B2 | 15 |
| CDC2/CDK1 | Cell division cycle 2, G1 to S and G2 to M | 10 |
| CDC25A | Cell division cycle 25A | 3 |
| CDC25B | Cell division cycle 25B | 20 |
| CDC25C | Cell division cycle 25C | 5 |
|
| Spindle checkpoint |
| BUB1 | BUB1 budding uninhibited by benzimidazoles 1 homolog | 2 |
| BUB1B/BUBR1 | BUB1 budding uninhibited by benzimidazoles 1 homolog beta | 15 |
| CENPA | Centromere protein A | 2 |
| CENPE | Centromere protein E | 4 |
| CENPH | Centromere protein H | 5 |
| MAD2L1/MAD2 | MAD2 mitotic arrest deficient-like 1 | 4 |
|
| Cytoplasmic receptors |
| NALP5/NLRP5/MATER | NLR family, pyrin domain containing 5 | 19 |
|
| APC/C complex, securin, cohesins |
| ANAPC1/APC1 | Anaphase promoting complex subunit 1 | 2 |
| ANAPC10/APC10 | Anaphase promoting complex subunit 10 | 4 |
| CDC20 | CDC20 cell division cycle 20 | 1 |
| PTTG1 | Pituitary tumor-transforming 1 | 5 |
| PTTG3 | Pituitary tumor-transforming 3 (meiosis) | 8 |
| STAG3 | Stromal antigen 3 (meiosis) | 7 |
|
| Epigenetic remodeling |
| DNMT1 | DMA (cytosine-5-)-methyltransferase 1 | 19 |
| DNMT3B | DMA (cytosine-5-)-methyltransferase 3 beta | 20 |
| HDAC9 | Histone deacetylase 9 | 7 |
| H1FOO | H1 histone family, member O, oocyte-specific | 3 |
| HCAP-G | Chromosome condensation protein G | 4 |
|
| Meiosis, miscellaneous |
| AKAP1 | A kinase (PRKA) anchor protein 1 | 17 |
| MCM3 | MCM3 minichromosome maintenance deficient 3 | 6 |
| MOS | v-mos Moloney murine sarcoma viral oncogene homolog | 8 |
| REC8 | REC8 homolog (yeast) | 14 |
| STAG3 | Stromal antigen 3 | 7 |
| FMN2 | Formin 2 | 1 |
| SYCP1 | Synaptonemal complex protein 1 | 1 |
| SYCP2 | Synaptonemal complex protein 2 | 20 |
| SYCP3 | Synaptonemal complex protein 3 | 12 |
| SMC3 | Structural maintenance of chromosomes 3 | 10 |
| SMC1B | Structural maintenance of chromosomes 1B | 22 |
| STRA8 | Stimulated by retinoic acid gene 8 homolog (mouse) | 7 |
| MLH1 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 3 |
| DMC1 | DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) | 22 |
| PELO | Pelota homolog (Drosophila) | 5 |
| WEE2 | WEE1 homolog 2 (S. pombe) | 7 |
| SGOL2 | Shugoshin-like 2 (S. pombe) | 2 |
| PPP2CA | Protein phosphatase 2, catalytic subunit, alpha isozyme | 5 |
| SPAG16 | Sperm associated antigen 16 | 2 |
| TUBB4Q | Tubulin, beta polypeptide 4, member Q | 4 |
| FBXO5/EMI1 | F-box protein 5 | 6 |
| AURKC | Aurora kinase C | 19 |
|
| Extracellular matrix, growth factors, cell surface, signaling |
| BMP15 | Bone morphogenetic protein 15 | X |
| BMP6 | Bone morphogenetic protein 6 | 6 |
| GDF9 | Growth differentiation factor 9 | 5 |
| FGFR2 | Fibroblast growth factor receptor 2 | 10 |
| FGF9 | Fibroblast growth factor 9 (glia-activating factor) | 13 |
| FGF14 | Fibroblast growth factor 14 | 13 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 4 |
| IL4 | Interleukin 4 | 5 |
| TNFSF13/APRIL | Tumor necrosis factor superfamily, member 13 v-erb-a erythroblastic leukemia viral oncogene | 17 |
| ERBB4 | Homolog 4 | 2 |
| FZD3 | Frizzled homolog 3 | 8 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 7 |
| GPR39 | G protein-coupled receptor 39 | 2 |
| GPR51 | G protein-coupled receptor 51 | 9 |
| GPR126 | G protein-coupled receptor 126 | 6 |
| GPR143 | G protein-coupled receptor 143 | X |
| GPR160 | G protein-coupled receptor 160 | 3 |
| ZP1 | Zona pellucida glycoprotein 1 (sperm receptor) | 11 |
| ZP2 | Zona pellucida glycoprotein 2 (sperm receptor) | 16 |
| ZP3 | Zona pellucida glycoprotein 3 (sperm receptor) | 7 |
| ZP4 | Zona pellucida glycoprotein 4 | 1 |
| SLC5A11 | Solute carrier family 5 (sodium/glucose cotransporter), member 11 | 16 |
| SOCS7 | Suppressor of cytokine signaling 7 | 17 |
|
| Transcription factors, oogenesis, folliculogenesis |
| FIGLA | Folliculogenesis specific basic helix-loop-helix | 2 |
| POU5F1 | POU class 5 homeobox 1 | 6 |
| NOBOX | NOBOX oogenesis homeobox | 7 |
| BNC1 | Basonuclin 1 | 15 |
| GCNF/NR6A1 | Nuclear receptor subfamily 6, group A, member 1 | 9 |
| SOX15 | SRY (sex determining region Y)-box 15 | 17 |
| SOX30 | SRY (sex determining region Y)-box 30 | 5 |
| OTX2 | Orthodenticle homolog 2 (Drosophila) | 14 |
| FOXR1 | Forkhead box R1 | 11 |
| JARID2 | Jumonji, AT rich interactive domain 2 | 6 |
|
| Chromatin reprogramming |
| NPM2 | Nucleophosmin/nucleoplasmin 2 | 8 |
|
| Postreplicative DNA mismatch repair system |
| MSH2 | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 2 |
|
| Oolema receptor (oocyte-sperm adhesion) |
| ASTL | Astacin-like metalloendopeptidase (M12 family) | 2 |
|
| Imprinted genes |
| MEST | Mesoderm specific transcript homolog | 7 |
|
| Apoptosis |
| BNIP1 | BCL2/adenovirus E1B 19 kDa interacting protein 1 | 5 |
| BIRC5 | Baculoviral IAP repeat-containing 5 (survivin) | 17 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) | 15 |
|
