|
Genes significantly overexpressed in oocytes |
Gene symbol | Gene title | Chromosome |
|
Gamete markers |
DAZL | Deleted in azoospermia-like | 3 |
DDX4/VASA | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 5 |
DPPA3/STELLA | Developmental pluripotency associated 3 | 12 |
|
Embryogenesis, pluripotency, self-renewal, proliferation, development |
ZAR1 | Zygote arrest 1 | 4 |
PUM1 | Pumilio homolog 1 (Drosophila) | 1 |
PUM2 | Pumilio homolog 2 (Drosophila) | 2 |
NANOS1 | Nanos homolog 1 (Drosophila) | 10 |
NANOG | Nanog homeobox | 12 |
SOX2 | SRY (sex determining region Y)-box 2 | 3 |
SALL2 | Sal-like 2 (Drosophila) | 14 |
KLF4 | Kruppel-like factor 4 (gut) | 9 |
LIN28B | Lin-28 homolog B (C. elegans) | 6 |
|
Maturation promoting and related factors |
CCNB1 | Cyclin B1 | 5 |
CCNB2 | Cyclin B2 | 15 |
CDC2/CDK1 | Cell division cycle 2, G1 to S and G2 to M | 10 |
CDC25A | Cell division cycle 25A | 3 |
CDC25B | Cell division cycle 25B | 20 |
CDC25C | Cell division cycle 25C | 5 |
|
Spindle checkpoint |
BUB1 | BUB1 budding uninhibited by benzimidazoles 1 homolog | 2 |
BUB1B/BUBR1 | BUB1 budding uninhibited by benzimidazoles 1 homolog beta | 15 |
CENPA | Centromere protein A | 2 |
CENPE | Centromere protein E | 4 |
CENPH | Centromere protein H | 5 |
MAD2L1/MAD2 | MAD2 mitotic arrest deficient-like 1 | 4 |
|
Cytoplasmic receptors |
NALP5/NLRP5/MATER | NLR family, pyrin domain containing 5 | 19 |
|
APC/C complex, securin, cohesins |
ANAPC1/APC1 | Anaphase promoting complex subunit 1 | 2 |
ANAPC10/APC10 | Anaphase promoting complex subunit 10 | 4 |
CDC20 | CDC20 cell division cycle 20 | 1 |
PTTG1 | Pituitary tumor-transforming 1 | 5 |
PTTG3 | Pituitary tumor-transforming 3 (meiosis) | 8 |
STAG3 | Stromal antigen 3 (meiosis) | 7 |
|
Epigenetic remodeling |
DNMT1 | DMA (cytosine-5-)-methyltransferase 1 | 19 |
DNMT3B | DMA (cytosine-5-)-methyltransferase 3 beta | 20 |
HDAC9 | Histone deacetylase 9 | 7 |
H1FOO | H1 histone family, member O, oocyte-specific | 3 |
HCAP-G | Chromosome condensation protein G | 4 |
|
Meiosis, miscellaneous |
AKAP1 | A kinase (PRKA) anchor protein 1 | 17 |
MCM3 | MCM3 minichromosome maintenance deficient 3 | 6 |
MOS | v-mos Moloney murine sarcoma viral oncogene homolog | 8 |
REC8 | REC8 homolog (yeast) | 14 |
STAG3 | Stromal antigen 3 | 7 |
FMN2 | Formin 2 | 1 |
SYCP1 | Synaptonemal complex protein 1 | 1 |
SYCP2 | Synaptonemal complex protein 2 | 20 |
SYCP3 | Synaptonemal complex protein 3 | 12 |
SMC3 | Structural maintenance of chromosomes 3 | 10 |
SMC1B | Structural maintenance of chromosomes 1B | 22 |
STRA8 | Stimulated by retinoic acid gene 8 homolog (mouse) | 7 |
MLH1 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | 3 |
DMC1 | DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) | 22 |
PELO | Pelota homolog (Drosophila) | 5 |
WEE2 | WEE1 homolog 2 (S. pombe) | 7 |
SGOL2 | Shugoshin-like 2 (S. pombe) | 2 |
PPP2CA | Protein phosphatase 2, catalytic subunit, alpha isozyme | 5 |
SPAG16 | Sperm associated antigen 16 | 2 |
TUBB4Q | Tubulin, beta polypeptide 4, member Q | 4 |
FBXO5/EMI1 | F-box protein 5 | 6 |
AURKC | Aurora kinase C | 19 |
|
Extracellular matrix, growth factors, cell surface, signaling |
BMP15 | Bone morphogenetic protein 15 | X |
BMP6 | Bone morphogenetic protein 6 | 6 |
GDF9 | Growth differentiation factor 9 | 5 |
FGFR2 | Fibroblast growth factor receptor 2 | 10 |
FGF9 | Fibroblast growth factor 9 (glia-activating factor) | 13 |
FGF14 | Fibroblast growth factor 14 | 13 |
KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 4 |
IL4 | Interleukin 4 | 5 |
TNFSF13/APRIL | Tumor necrosis factor superfamily, member 13 v-erb-a erythroblastic leukemia viral oncogene | 17 |
ERBB4 | Homolog 4 | 2 |
FZD3 | Frizzled homolog 3 | 8 |
GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 7 |
GPR39 | G protein-coupled receptor 39 | 2 |
GPR51 | G protein-coupled receptor 51 | 9 |
GPR126 | G protein-coupled receptor 126 | 6 |
GPR143 | G protein-coupled receptor 143 | X |
GPR160 | G protein-coupled receptor 160 | 3 |
ZP1 | Zona pellucida glycoprotein 1 (sperm receptor) | 11 |
ZP2 | Zona pellucida glycoprotein 2 (sperm receptor) | 16 |
ZP3 | Zona pellucida glycoprotein 3 (sperm receptor) | 7 |
ZP4 | Zona pellucida glycoprotein 4 | 1 |
SLC5A11 | Solute carrier family 5 (sodium/glucose cotransporter), member 11 | 16 |
SOCS7 | Suppressor of cytokine signaling 7 | 17 |
|
Transcription factors, oogenesis, folliculogenesis |
FIGLA | Folliculogenesis specific basic helix-loop-helix | 2 |
POU5F1 | POU class 5 homeobox 1 | 6 |
NOBOX | NOBOX oogenesis homeobox | 7 |
BNC1 | Basonuclin 1 | 15 |
GCNF/NR6A1 | Nuclear receptor subfamily 6, group A, member 1 | 9 |
SOX15 | SRY (sex determining region Y)-box 15 | 17 |
SOX30 | SRY (sex determining region Y)-box 30 | 5 |
OTX2 | Orthodenticle homolog 2 (Drosophila) | 14 |
FOXR1 | Forkhead box R1 | 11 |
JARID2 | Jumonji, AT rich interactive domain 2 | 6 |
|
Chromatin reprogramming |
NPM2 | Nucleophosmin/nucleoplasmin 2 | 8 |
|
Postreplicative DNA mismatch repair system |
MSH2 | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 2 |
|
Oolema receptor (oocyte-sperm adhesion) |
ASTL | Astacin-like metalloendopeptidase (M12 family) | 2 |
|
Imprinted genes |
MEST | Mesoderm specific transcript homolog | 7 |
|
Apoptosis |
BNIP1 | BCL2/adenovirus E1B 19 kDa interacting protein 1 | 5 |
BIRC5 | Baculoviral IAP repeat-containing 5 (survivin) | 17 |
BCL2L10 | BCL2-like 10 (apoptosis facilitator) | 15 |
|