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BioMed Research International
Volume 2013 (2013), Article ID 901975, 7 pages
Clinical Study

Risk Factors for High-Titer Inhibitor Development in Children with Hemophilia A: Results of a Cohort Study

1Gerinnungszentrum Rhein-Ruhr (GZRR), 47051 Duisburg, Germany
2Department of Pediatrics, University Hospital of Munich, 80337 Munich, Germany
3Department of Pediatric Hematology/Oncology, University Hospital of Frankfurt, 60590 Frankfurt, Germany
4Outpatient Hemophilia Treatment Center, 23564 Lubbock, Germany
5Department of Pediatric Hematology/Oncology, Charite, 13353 Berlin, Germany
6The Israel National Hemophilia Centre, Sheba Medical Centre, Tel-Hashomer and the Sackler Medical School, Tel Aviv, 52621 Tel-Hashomer, Israel
7Department of Pediatrics, University Hospital of Münster, 48149 Münster, Germany
8Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada L85 4K1
9Thrombosis & Hemophilia Treatment Center, Institute of Clinical Chemistry, University Hospital of Kiel, 24105 Kiel, Germany

Received 25 June 2013; Revised 30 August 2013; Accepted 31 August 2013

Academic Editor: Saulius Butenas

Copyright © 2013 Susan Halimeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Table: Subgroup analysis of patients (1) with severe HA and (2) derived from Germany.

  1. Supplementary Table