Metabolism, Physiological Role, and Clinical Implications of Sphingolipids in Gastrointestinal Tract

Figure 3

Changes (increase—blue color, decrease—red color) in activities of enzymes engaged in sphingolipids metabolism in colorectal cancer (adapted from [2, 3]). CDase: ceramidase; SMase: sphingomyelinase; S1P lyase: sphingosine-1-phosphate lyase; SPHK: sphingosine kinase; SPT: serine palmitoyl transferase.