Research Article

Inflammatory Bowel Disease Therapies and Gut Function in a Colitis Mouse Model

Table 1

Population, sex, and group description of IL-10āˆ’/āˆ’ mice on a C57BL/6 background.

Group no.Group descriptionTotal number of mice

1Noninfeced control group; no infection and no treatment (66.7% female)9 (killed time 0)

Treatmentsweek 2week 4

2Infected control group; treatment: sterilized water ( ; 58.3% female)66
3 1HC group; treatment: HC ( ; 41.7% female)6 26
4 3EEN group; treatment: 4PF ( ; 46.2% female)85
5 5MNZ group; treatment: MNZ ( ; 46.2% female)76
6EEN + MNZ group; treatment: a combination of PF and MNZ ( . 50% female)66

; 2mice in this group were euthanized at week 3 because of severe diarrhea, dehydration, and weight loss (their indexes were compared to those of other groups at week 4 throughout this study); 3exclusive enteral nutrition; 4polymeric formula; 5metronidazole.