Inflammatory Bowel Disease Therapies and Gut Function in a Colitis Mouse Model
Table 1
Population, sex, and group description of IL-10ā/ā mice on a C57BL/6 background.
Group no.
Group description
Total number of mice
1
Noninfeced control group; no infection and no treatment (66.7% female)
9 (killed time 0)
Treatments
week 2
week 4
2
Infected control group; treatment: sterilized water (; 58.3% female)
6
6
3
1HC group; treatment: HC (; 41.7% female)
6
26
4
3EEN group; treatment: 4PF (; 46.2% female)
8
5
5
5MNZ group; treatment: MNZ (; 46.2% female)
7
6
6
EEN + MNZ group; treatment: a combination of PF and MNZ (. 50% female)
6
6
; 2mice in this group were euthanized at week 3 because of severe diarrhea, dehydration, and weight loss (their indexes were compared to those of other groups at week 4 throughout this study); 3exclusive enteral nutrition; 4polymeric formula; 5metronidazole.