Robust Cell Size Checkpoint from Spatiotemporal Positive Feedback Loop in Fission Yeast
Figure 2
(a)(c)(e) The steady state of MPF with different given rates of synthesis () and different given concentrations of Cdr (cdr). The dark blue areas indicate the stable steady state of MPF, and the dark red areas indicate the unstable steady state of MPF. (a) The green vertical plane represents the variation in the rates of Cdc13 synthesis as the cell grows for a fixed concentration of Cdr. The plane intersects with the bent surface, forming an S-shaped curve. (b) When this curve is displayed in two-dimensional space, it represents the relationship between MPF and the rate of synthesis. (c) The green vertical plane represents the variation in the concentration of Cdr as the cell grows for a fixed rate of Cdc13 synthesis. The plane intersects with the bent surface, forming an S-shaped curve. (d) When this curve is displayed in two-dimensional space, it represents the relationship between MPF and the concentration of Cdr. (e) The vertical green surface represents the relationship between the concentration of Cdr and the rate of synthesis of Cdc13 as the cell grows. The vertical green surface intersects with the bent surface, forming an S-shaped curve. (f) When this curve is displayed in two-dimensional space, it represents the relationship between MPF and cell size.
