Endoplasmic Reticulum Stress-Mediated Hippocampal Neuron Apoptosis Involved in Diabetic Cognitive Impairment

<table>CHOP positive neurons in dentate gyrus of the hippocampus. (400x): (a) a control rat, (b) a diabetic rat, (c) the number of CHOP positive neurons and (d) the optical density of CHOP positive neurons. The immunoreactivity of CHOP protein was visualized in brown granular immunostain pattern and the brown stain indicates increased CHOP activity in diabetic rats (b) compared with the control rats (a). <svg height="13.95" id="M25" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 69.150002 13.95" width="69.150002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus control rats.</table>

BioMed Research International

fig3

Figure 3

Figure 3: Endoplasmic Reticulum Stress-Mediated Hippocampal Neuron Apoptosis Involved in Diabetic Cognitive Impairment 