BioMed Research International / 2013 / Article / Fig 4

Research Article

Different Effects of the Immunomodulatory Drug GMDP Immobilized onto Aminopropyl Modified and Unmodified Mesoporous Silica Nanoparticles upon Peritoneal Macrophages of Women with Endometriosis

Figure 4

The influence of GMPD, immobilized upon the different silica nanoparticles, and free GMPD on the NOD2, RAGE, and SOCS1 mRNAs expression by peritoneal macrophages of women with endometriosis. (a) The influence of GMPD on NOD2 mRNA expression. (b) The influence of GMDP on RAGE mRNA expression. (c) The influence of GMPD on SOCS1 mRNA expression. (Notes: C—control (incubation in RPMI 1640 medium only), GMDP—free form of GMDP, AMNPs-GMDP, immobilized onto the AMNPs, UMNPs-GMDP, immobilized onto the UMNPs, results are presented as the mean ± standard error; *differences in comparison to the control values are statistically significant, ).