Antituberculosis: Synthesis and Antimycobacterial Activity of Novel Benzimidazole Derivatives

Table 1

Physical properties and analytical results of compounds 5a–g.

Compound	R1	Formula	C/H/N calculated; (C/H/N found)	[M + H]	Yield (%)
5a		C31H35N5O4	68.74%/6.51%/12.93%; (68.61%/6.45%/13.12%)	514.2	63
5b		C31H34N5O4Cl	64.63%/5.95%/12.16%; (64.45%/5.93%/12.25%)	575.2	85
5c		C31H35N5O6	64.91%/6.15%/12.21%; (64.72%/6.07%/12.40%)	573.3	71
5d		C32H34N5O5F3	61.43%/5.48%/11.19%; (61.55%/5.40%/11.22%)	625.3	90
5e		C32H37N5O5	67.23%/6.52%/12.25%; (67.06%/6.42%/12.48%)	571.3	79
5f		C32H35N5O6	65.63%/6.02%/11.96%; (65.62%/6.02%/11.92%)	585.3	73
5g		C42H41N6O4F	70.77%/5.80%/11.79%; (70.52%/5.72%/12.08%)	712.3	66