BioMed Research International / 2013 / Article / Tab 1

Research Article

Deposition of Doxorubicin in Rats following Administration of Three Newly Synthesized Doxorubicin Conjugates

Table 1

Pharmacokinetic parameters of doxorubicin and its conjugates.

ParametersDOXDOX-LNAPEG-ami-DOXPEG-hyd-DOX
Free DOXTotal DOXFree DOXTotal DOXFree DOXTotal DOX

(h)
( g/mL/h)
CL (mL/h/Kg)
(mL/kg)

P < 0.05; P < 0.01, as compared with DOX formulation; P < 0.05, as compared with PEG-ami-DOX. ( ).