The Associated Ion between the VDR Gene Polymorphisms and Susceptibility to Hepatocellular Carcinoma and the Clinicopathological Features in Subjects Infected with HBV

Table 5

Association between VDR polymorphisms and the clinicopathological features in HCC subjects.

FokI C>T		Tumor size			Adjusted OR	95% CI		Adjusted 𝑃 value
	<30 mm	%	>30 mm	%
CC	55	25.00%	57	26.39%	1
CT	108	49.09%	109	50.46%	1.027	0.651	1.62	0.543
TT	57	25.91%	50	23.15%	1.181	0.695	2.008	0.068
		Cancer stage
	III + IV		I + II
CC	43	18.53%	64	29.91%	1
CT	109	46.98%	99	46.26%	1.639	1.021	2.629	0.054
TT	70	34.48%	51	23.83%	2.335	1.385	3.936	0.001
		Liver cirrhosis history
	Presence		Absence
CC	40	18.78%	67	30.04%	1
CT	92	43.19%	106	47.53%	1.454	0.899	2.352	0.127
TT	81	38.03%	50	22.42%	2.714	1.602	4.596	<0.001
		Lymph node metastasis
	Presence		Absence
CC	43	18.45%	64	29.77%	1
CT	96	41.20%	102	47.44%	1.401	0.87	2.256	0.038
TT	77	33.05%	54	25.12%	2.122	1.262	3.57	0.004
		Portal invasion
	Presence		Absence
CC	53	25.48%	62	27.19%	1
CT	110	52.88%	102	44.74%	1.260	0.843	1.991	0.326
TT	45	21.63%	64	28.07%	0.820	0.482	1.411	0.470
		Heavy alcohol intake, 𝑛 (%)
	Yes		No
CC	43	28.29%	67	27.02%	1.000
CT	75	49.34%	126	50.81%	0.927	0.575	1.496	0.757
TT	34	22.37%	55	22.18%	0.963	0.543	1.710	0.898