Table 3: Cross-trial comparison.

V325REAL-2
DCFCFECFECXEOFEOXDOX

Median age (yr)55556564616248
Range (yr)26~7925~7622~8325~8233~7825~8027~72
Metastasis (%)969779.576.87775.783.8
One least dose reduction (%)41.236.2////43.2
OS (m)9.28.69.99.99.311.211.9
PFS (m)5.63.76.26.76.576.5
RR (%)372540.746.442.447.929.7
CR (%)214.14.22.63.92.7
PR (%)352436.642.239.84427
SD (%)3031////62.2
Adverse events
 Leukopenia 6531////37.8
 Neutropenia 825741.751.129.927.637.8
 Fabric neutropenia29129.36.78.57.810.8
 Hand-foot syndrome//4.310.32.73.18.1
 Nausea 141710.27.713.811.45.4
 Vomit 14175.4
 Diarrhea 1982.65.110.711.92.7
 Fatigue 19141615.512.924.927