Evaluation of In Vivo Wound Healing Activity of Bacopa monniera on Different Wound Model in Rats

Table 2

Effect of BME and VTE on wet granulation tissue weight, protein, free radicals (LPO and NO), antioxidants (GSH, SOD, and CAT), and myeloperoxidase (MPO).

Oral treatment; (mg/kg, od × 10 day)	Wet tissue; mg/100 g bw	Protein; mg/g tissue	Antioxidants			Free radicals		Myeloperoxidase
			GSH; nM/mg protein	SOD; IU/mg protein	CAT; mU/mg protein	LPO; nM/mg protein	NO; nM/mg protein	MPO; mU/mg protein
Control 0.5% CMC	359.3 ± 18.3	48.6 ± 2.75	20.7 ± 1.17	0.41 ± 0.07	42.9 ± 1.84	6.33 ± 0.50	36.8 ± 4.53	24.1 ± 0.55
BME 25	422.7 ± 18.1^a	57.7 ± 2.05^a	24.6 ± 1.11^a	0.72 ± 0.02^b	151.6 ± 0.68^c	3.24 ± 0.26^c	15.3 ± 0.87^c	19.3 ± 0.29^c
VTE 200	461.5 ± 11.5^b	59.1 ± 3.40^a	24.5 ± 0.88^a	0.79 ± 0.04^c	210.4 ± 0.84^c	1.78 ± 0.15^c	15.2 ± 1.53^b	14.6 ± 0.37^c

Values are mean ± SEM of 6 rats in each group. ^a𝑃<0.05, ^b𝑃<0.01, and ^c𝑃<0.001 compared to respective control group (statistical analysis was done by one-way analysis of variance followed by Dunnett’s test for multiple comparisons).