Single Nucleotide Polymorphism in the Promoter of the Human Interleukin-13 Gene Is Associated with Asthma in Malaysian Adults

Table 4

Relationship between the SNP in the human Il-13 gene and production of IL-13 by the Con A-stimulated peripheral blood leucocytes.

SNP	Genotype	Production of IL-13 (pg/mL)		𝑃 value^a
		Asthmatic patients (mean ± SD)	Control subjects (mean ± SD)
−1111C>T	CC	345.41±117.71	222.63±93.30	<0.001
	CT	252.96±119.40	208.31±107.64	0.089
	TT	295.92±95.70	158.05±65.40	<0.001
4257G>A	GG	264.16±93.50	209.44±91.54	0.068
	GA	285.62±93.50	215.25±103.46	0.011
	AA	300.41±116.75	182.26±92.72	0.008

aMann-Whitney test.
SD: standard deviation.