Neuroprotective Activity of Thioctic Acid in Central Nervous System Lesions Consequent to Peripheral Nerve Injury
Figure 2
Western blot analysis of plasma oxidized protein (a) and densitometric analysis of these bands (b). The system revealed the oxidized plasmatic proteins with a range of molecular weight between 250 KDa and 55 KDa. (A) Control Sham-operated WKY rats, (B) control Sham-operated SHRs, (C) control CCI SHRs, (D) CCI SHRs treated with ()-thioctic acid 125 μmol/kg/day, (E) CCI SHRs treated with ()-thioctic acid 250 μmol/kg/day, (F) CCI SHRs treated with (+)-thioctic acid 125 μmol/kg/day, (G) CCI SHRs treated with (−)-thioctic acid 125 μmol/kg/day, and (H) CCI SHRs treated with pregabalin 300 μmol/kg/day (H). Data of densitometric analysis were expressed as arbitrary units. ** versus SHR Sham-operated control rats; *** versus control CCI SHR.
