Research Article

Antibacterial Activity of Defensin PaDef from Avocado Fruit (Persea americana var. drymifolia) Expressed in Endothelial Cells against Escherichia coli and Staphylococcus aureus

Figure 1

Characteristics of defensin PaDef from Persea americana var. drymifolia. (a) Alignment of the defensin PaDef with defensin holotype type 1 (R. sativus Rs-AFP1) and defensin holotype type 2 (N. alata NaD1). In red, the 8 conserved cysteines are indicated. (b) Prediction of disulfide bridges of defensin PaDef. The pattern was determined using the DISULFIND predictor. (c) Structural organization of defensin PaDef peptide. Left: secondary structure showing the characteristic CS motif of defensins. Red arrows indicate the -sheets. Right: homology model of defensin PaDef peptide. Model was created using Rs-AFP1 (Protein Data Bank: 1AYJ) as template.
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