Effects of a Pragmatic Lifestyle Intervention for Reducing Body Mass in Obese Adults with Obstructive Sleep Apnoea: A Randomised Controlled Trial
Table 2
Raw data by groups and adjusted mean differences in change at intervention end-point and followup.
Variable
Intervention end-point
Followup
(week 13)
(week 26)
Control
Intervention
Adjusted mean diff. (95% CI)
Control
Intervention
Adjusted mean diff. (95% CI)
Anthropometry
Body mass (kg)
117.9 ± 21.0
115.2 ± 24.3
−1.8 (−3.0, −0.5)
0.006
118.1 ± 21.0
115.1 ± 24.4
−2.0 (−3.5, −0.5)
0.010
Body mass index (kg·m−2)
39.8 ± 6.8
38.0 ± 6.9
−0.8 (−1.3, −0.3)
0.002
39.8 ± 6.7
37.9 ± 6.9
−0.9 (−1.5, −0.3)
0.002
Body fat (%)
40 ± 9
37 ± 8
−1 (−2, 0)
0.044
40 ± 9
38 ± 8
−1 (−2, 0)
0.033
Hip circumference (cm)
128 ± 15
123 ± 15
−1 (−2, 0)
0.093
128 ± 15
122 ± 15
−2 (−3, 0)
0.020
Waist circumference (cm)
127 ± 15
123 ± 16
−2 (−4, 0)
0.117
127 ± 15
123 ± 15
−2 (−4, 1)
0.143
Hip circumference (cm)
128 ± 15
123 ± 15
−1 (−2, 0)
0.093
128 ± 15
122 ± 15
−2 (−3, 0)
0.020
Cardiometabolic
Resting heart rate (beats·min−1)
66 ± 12
64 ± 12
−5 (−9, −2)
0.002
62 ± 9
63 ± 10
−2 (−6, 1)
0.165
Resting systolic BP (mmHg)
127 ± 13
130 ± 13
0 (−5, 4)
0.893
131 ± 14
133 ± 16
−2 (−7, 4)
0.534
Resting diastolic BP (mmHg)
72 ± 8
74 ± 9
−1 (−4, 2)
0.590
75 ± 8
76 ± 10
−1 (−4, 2)
0.539
Serum cholesterol (mmol·L−1)
4.8 3.2, 6.4
4.8 3.5, 6.1
0.1 (−0.2, 0.3)
0.575
4.4 2.5, 6.3
4.6 3.6, 5.5
−0.1 (−0.5, 0.3)
0.645
Serum HDL (mmol·L−1)
1.2 ± 0.2
1.2 ± 0.3
0.0 (−0.1, 0.9)
0.569
1.2 ± 0.3
1.2 ± 0.2
−0.1 (−0.2, 0)
0.241
Serum LDL (mmol·L−1)
2.7 ± 0.8
2.9 ± 1
0 (−0.2, 0.3)
0.731
2.6 ± 0.9
2.8 ± 0.9
0 (−0.3, 0.3)
0.814
Serum CRP (mg·L−1)
3.3 0.1, 6.5
1.4 −0.7, 3.5
−1.3 (−2.4, −0.2)
0.028
3.2 −2.1, 8.5
1.8 0.6, 3
−1.3 (−2.5, −0.1)
0.037
Serum glucose (mmol·L−1)
5.7 ± 1.9
4.8 ± 0.5
−0.3 (−0.9, 0.2)
0.224
5.7 ± 1.9
4.8 ± 0.8
−0.3 (−0.9, 0.3)
0.267
ISWT
ISWD (m)
475 ± 250
724 ± 193
95 (50, 139)
<0.001
471 ± 240
737 ± 179
132 (90, 175)
<0.001
Quality of life
EQVAS
63 ± 19
60 ± 20
3 (−4, 10)
0.385
69 ± 18
72 ± 16
9 (2, 16)
0.017
Data are presented as mean ± SD or median IQR. BP: blood pressure; HDL: high-density lipoprotein; LDL: low-density lipoprotein; CRP: C-reactive protein; ISWT: incremental shuttle walk test; ISWD: incremental shuttle walk distance; RPE: Borg rating of perceived exertion; EQVAS: EuroQol Visual Analogue Scale; : value adjusted for baseline score.
