Research Article
Relationship between CCR and NT-proBNP in Chinese HF Patients, and Their Correlations with Severity of HF
Table 1
Characteristics of the control, NYHA classification 1-2, and 3-4 groups.
| | Groups | Control ( = 135) | 1-2 ( = 79) | 3-4 ( = 122) | value | value |
| | Age, year (mean ± SD) | 65.84 ± 15.95 | 69.91 ± 13.14 | 68.27 ± 13.36 | 2.14 | 0.12 | | Male, % () | 47.40 (64/135) | 54.43 (43/79) | 63.93 (78/122) | 3.59 | 0.03 | | BMI, kg/m2 (mean ± SD) | 23.48 ± 3.69 | 24.19 ± 4.31 | 24.05 ± 4.22 | 1.13 | 0.33 | | Current smokers, % () | 27.40 (37/135) | 29.11 (23/79) | 17.21 (21/122) | 0.55 | 0.58 | | Hypertension, % () | 49.63 (67/135) | 75.94 (60/79) | 71.31 (87/122) | 10.39 | 0.00 | | Diabetes, % () | 16.30 (22/135) | 30.38 (24/79) | 38.52 (47/122) | 8.43 | 0.00 | | NT-proBNP, pg/mL (mean ± SD) | 78.83 ± 15.27 | 1611.54 ± 171.24 | 3162.19 ± 453.21 | 260.18 | 0.00 | | CCR, mL/min (mean ± SD) | 89.94 ± 16.39 | 59.43 ± 19.57 | 53.57 ± 17.41 | 154.87 | 0.00 | | Cr, mg/dL (mean ± SD) | 0.67 ± 0.15 | 1.07 ± 0.25 | 1.16 ± 0.23 | 195.55 | 0.00 | | UA, umol/L (mean ± SD) | 299.22 ± 56.12 | 418.91 ± 49.21 | 471.54 ± 64.72 | 88.80 | 0.00 | | LVEDD, mm (mean ± SD) | 45.21 ± 3.86 | 50.89 ± 6.65 | 52.85 ± 8.71 | 45.40 | 0.00 |
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BMI: body mass index; CCR: creatinine clearance rate; Cr: creatinine; LVEDD: left ventricular end-diastolic diameter; NT-proBNP: N-terminal pro-B-type natriuretic peptide; NYHA: New York Heart Association; UA: uric acid.
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