Emodin Augments Cisplatin Cytotoxicity in Platinum-Resistant Ovarian Cancer Cells via ROS-Dependent MRP1 Downregulation

<div>Expression of MRP1 mRNA in COC1/DDP cells exposed to cDDP or emodin. RT-PCR analysis was performed to assess MRP1 mRNA levels expressed as the fold change relative to that in the untreated control cells after normalization to GAPDH. 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BioMed Research International

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Figure 5

Figure 5: Emodin Augments Cisplatin Cytotoxicity in Platinum-Resistant Ovarian Cancer Cells via ROS-Dependent MRP1 Downregulation 