Quantifying Cerebellum Grey Matter and White Matter Perfusion Using Pulsed Arterial Spin Labeling
Figure 1
Sequence diagrams for FAIR ASST (a) and PICORE (b) and spatial definitions for different slabs of FAIR ASST (c) and PICORE (d). Imaging section presaturation pulses (a, b in pink) were played out before the inversion RF pulses (in red); the imaging section slabs for the presaturations are presented in pink (c, d). Inferior saturation pulses and the corresponding saturation slab are indicated by dark blue. Superior tagging suppression pulses and the corresponding saturation slab, for FAIR ASST only, are displayed in cyan (a, c). For FAIR ASST (a, c), the stronger gradient (pink) for the imaging section control inversion and the weaker gradient (red) for the spatially confined labeling inversion are superposed on the sequence diagram and further denoted by the legends beneath the sequence diagram. For PICORE (b, d), the labeling was achieved by using proximal inversion (red) 10 mm below the imaging slab (green); in the labeling experiment (b, top), the slice-selective gradient was played out with an RF inversion pulse to create the proximal inversion slab (d), while in the control experiment (b, bottom), the gradient was played out before the control off-resonance RF inversion pulse, to control for possible gradient eddy current effects. The imaging slab was positioned to make the first inferior imaging slice cover the inferior edge of the cerebellum (c, d).
