Cardioprotective Effects of Osteopontin-1 during Development of Murine Ischemic Cardiomyopathy

<table>Ischemic OPN<sup>−</sup>/<sup>−</sup>-hearts show different expression of antioxidative mediators. mRNA-expression of antioxidative mediators (a) heme oxygenase- (HMOX-) 1 and (b) glutathione peroxidase- (GPX-) 1. mRNA-expression of zinc-storage proteins (c) metallothionein (MT)-1 and (d) MT-2. <svg height="11.175" id="M27" style="vertical-align:-0.27588pt" version="1.1" viewbox="0 0 50.450001 11.175" width="50.450001" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>/group. RT-qPCR using Taqman and mRNA-expression is related to controls and GAPDH using comparative <svg height="11.425" id="M28" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 21.9125 11.425" width="21.9125" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>Ct-method. Bracket indicates <svg height="11.85" id="M29" style="vertical-align:-1.29163pt" version="1.1" viewbox="0 0 58.712502 11.85" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> between genotypes; <svg height="7.9250002" id="M30" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.1 7.9250002" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> indicates <svg height="11.85" id="M31" style="vertical-align:-1.29163pt" version="1.1" viewbox="0 0 58.712502 11.85" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus respective shams.</table>

BioMed Research International

fig3

Figure 3

Figure 3: Cardioprotective Effects of Osteopontin-1 during Development of Murine Ischemic Cardiomyopathy 