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BioMed Research International
Volume 2014, Article ID 127021, 11 pages
http://dx.doi.org/10.1155/2014/127021
Research Article

Evaluation of Anti-Candida Activity of Vitis vinifera L. Seed Extracts Obtained from Wine and Table Cultivars

1Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
2Department of Environmental Biology, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
3Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences and Multidisciplinary Centre of Research on Food Sciences, Florence University, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy
4CRA Agricultural Research Council, Research Unit for Enology in Central Italy, Via Cantina 12, Sperimentale 1, Velletri, 00049 Rome, Italy
5Department of Experimental Medicine, Microbiology Section, University of Perugia, Via Gambuli, Polo Unico Sant’Andrea delle Fratte, 06132 Perugia, Italy
6CRA Agricultural Research Council, Research Unit for Table Grapes and Wine Growing in Mediterranean Environment, Via Casamassima 148, Turi, 70010 Bari, Italy

Received 5 December 2013; Accepted 27 March 2014; Published 23 April 2014

Academic Editor: Aramati B. Reddy

Copyright © 2014 Giovanna Simonetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. D. Sobel, “Vulvovaginal candidosis,” The Lancet, vol. 369, no. 9577, pp. 1961–1971, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. D. Pietrella, A. Rachini, M. Pines et al., “TH17 cells and IL-17 in protective immunity to vaginal candidiasis,” PLoS ONE, vol. 6, no. 7, Article ID e22770, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Vecchiarelli, E. Pericolini, E. Gabrielli, and D. Pietrella, “New approaches in the development of a vaccine for mucosal candidiasis: progress and challenges,” Frontiers in Microbiology, vol. 3, p. 294, 2012. View at Publisher · View at Google Scholar
  4. G. del Gaudio, L. Lombardi, G. Maisetta et al., “Antifungal activity of the noncytotoxic human peptide hepcidin 20 against fluconazole-resistant Candida glabrata in human vaginal fluid,” Antimicrobial Agents and Chemotherapy, vol. 57, no. 9, pp. 4314–4321, 2013. View at Publisher · View at Google Scholar
  5. N. Tocci, G. Simonetti, F. D. D'Auria et al., “Root cultures of Hypericum perforatum subsp. angustifolium elicited with chitosan and production of xanthone-rich extracts with antifungal activity,” Applied Microbiology and Biotechnology, vol. 91, no. 4, pp. 977–987, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. N. Tocci, F. D'Auria, G. Simonetti et al., “A three-step culture system to increase the xanthone production and antifungal activity of Hypericum perforatum subsp. angustifolium in vitro roots,” Plant Physiology and Biochemistry, vol. 572, pp. 54–55, 2012. View at Google Scholar
  7. Á. M. Alonso Borbalán, L. Zorro, D. A. Guillén, and C. G. J. Barroso, “Study of the polyphenol content of red and white grape varieties by liquid chromatography-mass spectrometry and its relationship to antioxidant power,” Journal of Chromatography A, vol. 1012, no. 1, pp. 31–38, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Daglia, “Polyphenols as antimicrobial agents,” Current Opinion in Biotechnology, vol. 23, no. 2, pp. 174–181, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. G. Ozkan, S. Ulusoy, A. Orem et al., “Mechanisms of action: physiological effects. How does colistin-induced nephropathy develop and can it be treated?” Antimicrobial Agents and Chemotherapy, vol. 57, pp. 3463–3469, 2013. View at Google Scholar
  10. M. Hirasawa and K. Takada, “Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans,” Journal of Antimicrobial Chemotherapy, vol. 53, no. 2, pp. 225–229, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Cavaliere, P. Foglia, F. Marini, R. Samperi, D. Antonacci, and A. Laganà, “The interactive effects of irrigation, nitrogen fertilisation rate, delayed harvest and storage on the polyphenol content in red grape (Vitis vinifera) berries: a factorial experimental design,” Food Chemistry, vol. 122, no. 4, pp. 1176–1184, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Giorio and V. Nuzzo, “Leaf area, light environment, and gas exchange in Montepulciano grapevines trained to Tendone trellising system,” Plant Biosystems, vol. 146, pp. 322–333, 2012. View at Google Scholar
  13. B. Enjalbert, A. Rachini, G. Vediyappan et al., “A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections,” Infection and Immunity, vol. 77, no. 11, pp. 4847–4858, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. D. Pietrella, L. Angiolella, E. Vavala et al., “Beneficial effect of Mentha suaveolens essential oil in the treatment of vaginal candidiasis assessed by real-time monitoring of infection,” BMC Complementary and Alternative Medicine, vol. 11, article 18, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. Clinical and Laboratory Standards Institute, Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Approved Standard, Document M27-A3, CLSI, Wayne, Pa, USA, 3rd edition, 2008.
  16. Clinical and Laboratory Standards Institute, Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Third Informational Supplement, Document M27-S3, CLSI, Wayne, Pa, USA, 2008.
  17. K. S. Barker, S. Crisp, N. Wiederhold et al., “Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans,” Journal of Antimicrobial Chemotherapy, vol. 54, no. 2, pp. 376–385, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. P. L. Fidel Jr., M. E. Lynch, and J. D. Sobel, “Candida-specific Th1-type responsiveness in mice with experimental vaginal candidiasis,” Infection and Immunity, vol. 61, no. 10, pp. 4202–4207, 1993. View at Google Scholar · View at Scopus
  19. C. D'Enfert, A. Vecchiarelli, and A. J. P. Brown, “Bioluminescent fungi for real-time monitoring of fungal infections,” Virulence, vol. 1, no. 3, pp. 174–176, 2010. View at Google Scholar · View at Scopus
  20. K. Kondo, M. Kurihara, K. Fukuhara et al., “Conversion of procyanidin B-type (catechin dimer) to A-type: evidence for abstraction of C-2 hydrogen in catechin during radical oxidation,” Tetrahedron Letters, vol. 41, no. 4, pp. 485–488, 2000. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Hokkanen, S. Mattila, L. Jaakola, A. M. Pirttilä, and A. Tolonen, “Identification of phenolic compounds from lingonberry (Vaccinium vitis-idaea L.), Bilberry (v L.) andHybrid Bilberry (Vaccinium x intermedium Ruthe L.) Leaves,” Journal of Agricultural and Food Chemistry, vol. 57, no. 20, pp. 9437–9447, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. C. P. Passos, S. M. Cardoso, M. R. M. Domingues, P. Domingues, C. M. Silva, and M. A. Coimbra, “Evidence for galloylated type-A procyanidins in grape seeds,” Food Chemistry, vol. 105, no. 4, pp. 1457–1467, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. N. Chaves and J. C. Escudero, “Variation of flavonoid synthesis induced by ecological factors,” in Principles and Practices in Plant Ecology, S. Inderjit, K. M. M. Dakshini, and C. L. Foy, Eds., CRC Press, Boca Raton, Fla, USA, 1999. View at Google Scholar
  24. C. Cavaliere, P. Foglia, R. Gubbiotti, P. Sacchetti, R. Samperi, and A. Laganà, “Rapid-resolution liquid chromatography/mass spectrometry for determination and quantitation of polyphenols in grape berries,” Rapid Communications in Mass Spectrometry, vol. 22, no. 20, pp. 3089–3099, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. G. Pasqua, G. Simonetti, F. D. D’uria, A. R. Santamaria, D. Antonacci, and N. Mulinacci, Patent Pending Based on Italian Priority IT RM20100636 and Related to “Extracts obtained from Vitis vinifera seeds and/or pomace and/or green grapes and/or stalks and uses thereof as antifungal agents” PCT/IT 2011/000400, 2013.